JNNP Podcast

Brain atrophy and disability progression in multiple sclerosis patients

Dr Robert Zivadinov, Department of Neurology, School of Medicine and Biomedical Sciences, Buffalo Neuroimaging Analysis Center, discusses his paper which aimed to identify MRI biomarkers associated with long-term disability progression in patients with multiple sclerosis (MS), and to define the rate of evolution of global, tissue-specific and regional atrophy in patients with MS over long-term.
Read the full paper (for free): http://jnnp.bmj.com/content/85/10/1109.full

BNPA 2014: Joint hypermobilty and autonomic hyperactivity

Chis Butler, MRC Clinician Scientist and Honorary Consultant Neurologist at the University of Oxford, talks to Jessica Eccles, MRC Clinical Research Training Fellow, Brighton and Sussex Medical School, about her work into joint hypermobilty and autonomic hyperactivity, and their relevance to neurodevelopmental disorders.
Read the abstract: http://jnnp.bmj.com/content/85/8/e3.40.abstract
This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

BNPA 2014: Post-Ictal psychosis

Hugh Rickards, consultant in Neuropsychiatry and honorary reader in Neuropsychiatry at Birmingham University, talks to Georgy Pius, ST6 Trainee, North West Deanery, about his case-control study examining post-ictal psychosis.
Read the abstract: http://jnnp.bmj.com/content/85/8/e3.39.abstract
This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

BNPA 2014: TREM2 variants and risk of dementia

Chris Butler, MRC Clinician Scientist and Honorary Consultant Neurologist at the University of Oxford, talks to Catherine Slattery, Clinical Research Associate, Institute of Neurology, about her work looking at TREM2 and associated risk of dementia.
Read the abstract:
http://goo.gl/SkJVXr
This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

Neurosurgical procedures for psychiatric illness

This month, how to safely and ethically carry out stereotactic surgery for psychiatric illness.
Bart Nuttin, Department of Neurosurgery, University of Leuven, has put together pragmatic guidelines, with the input of international psychiatric and neurosurgical societies.Here he gives us an overview.
Read the guidelines in full: http://jnnp.bmj.com/content/85/9/1003.full

Can stress trigger Parkinson’s? And new criteria for frontotemporal dementia syndromes.

Does emotional stress trigger Parkinson's disease? Andrew Lees, Reta Lila Weston Institute of Neurological Studies, talks us through the evidence so far.And Glenda Halliday, Neuroscience Research Australia, and colleagues, have examined the clinical and pathological diagnostic implications of new criteria for frontotemporal dementia syndromes. She discusses the highlights.Read both the papers, for free:New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications http://goo.gl/87At72Can stress trigger Parkinson's disease? http://goo.gl/bS8igNListen to the PN podcast reviewing Michael J Fox's memoir, Lucky Man http://goo.gl/1XCpDP

HIV and multiple sclerosis: beginning to unravel a mystery

Julian Gold, professor in the department of neuroscience and trauma, Queen Mary, University of London, and senior staff specialist, Albion Centre, Prince of Wales Hospital, Sydney, discusses his paper which investigates whether or not HIV protects against developing MS.Read the paper, for free: HIV and lower risk of multiple sclerosis: beginning to unravel a mystery using a record-linked database study http://goo.gl/j0G3SR

BNPA 2014: Neuropsychiatry of social knowledge and moral motivation

JNNP editor Alan Carson asks Roland Zahn, senior clinical lecturer, King's College London, about the neuroanatomy of moral behaviour, particularly his work into the neural mechanism of moral emotion in depression.This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

DBS in essential tremor, and genetic counselling for ALS

This month, genetic counselling for amyotrophic lateral sclerosis (ALS). Adriano Chiò, Turin ALS Expert Center, ‘Rita Levi Montalcini’ University of Turin, tells us what it can and can't do, who should have it, and how to go about it.And deep brain stimulation for essential tremor. Joseph Jankovic, Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine, explains what his study on long-term outcomes reveals.Read the papers:Genetic counselling in ALS: facts, uncertainties and clinical suggestions http://goo.gl/bYaqtQThe safety and efficacy of thalamic deep brain stimulation in essential tremor: 10 years and beyond http://goo.gl/OhCsIh

Mortality and morbidity 15 years after hospital admission with mild head injury

Head injury is very common, and we know those admitted to hospital with a severe head injury have a high mortality rate in the proceeding year. However less is known about later mortality, and even less about late survival after mild head injury, which accounts for 95% of all head injuries.Tom McMillan, Institute of Health and Wellbeing, MVLS, University of Glasgow, and colleagues, have followed up patients 15 years after admission with a mild head injury, and recently published the results in JNNP.In this podcast, Alan Carson, JNNP associate editor, asks him what they found.Read the full paper:Mortality and morbidity 15 years after hospital admission with mild head injury: a prospective case-controlled population study http://goo.gl/9aTU4Z